Regulated gene expression for Huntington's disease therapy
In order to find new efficient and safe agents for gene delivery, the goal is to develop and produce already synthesized and designed novel charged amphiphiles on the basis of pyridinium derivates.
Topical dna (deoxyribose nucleic acid) patch vaccine therapy is a novel investigational medicinal product for the treatment of hiv/aids. We will conduct human trials for proof of concept of the antiviral efficacy on hiv+ drug naive and drug failing patients.
Development and validation of a blood group genotyping system based on dna microarray technology that could be applied to high throughput donor typing.
Development of aav5-gdnf gene technology platform for brain diseases, focusing in this project on proof of concept for huntington disease and multiple system atrophy.